TABLE 1.
Neutralizing antibody response to vaccination of healthy and HIV-1-infected individuals against influenza A virus infection
| Vaccinated individuals
|
Mean ± SD log10 N-EIA titer against the following strain on the indicated day:
|
||||||
|---|---|---|---|---|---|---|---|
| Subject category | CD4+ count (cells/μl) | No. of subjects on the following days:
|
|||||
| 0 | 30 | Taiwan H1N1
|
Beijing H3N2
|
||||
| 0 | 30 | 0 | 30 | ||||
| Not HIV-1 infected | 10 | 9 | 0.76 ± 0.60 | 3.38 ± 0.88 | 1.74 ± 0.48a | 3.51 ± 0.79a | |
| HIV-1 infected | ≥200 | 23 | 23 | 1.64 ± 1.22 | 3.37 ± 0.73 | 1.34 ± 0.36 | 2.28 ± 0.59 |
| HIV-1 infected | <200 | 28 | 28 | 1.23 ± 1.12 | 2.03 ± 1.02b | 1.34 ± 0.32 | 1.65 ± 0.53b |
a
Significantly higher mean N-EIA titer (P < 0.05) compared to those for the other cohorts determined at the same time point.
b
Significantly lower mean N-EIA titer (P < 0.05) compared to those for other cohorts for measurements at the same time point.