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. 2025 Jun 4;15(6):e093072. doi: 10.1136/bmjopen-2024-093072

Table 2. Summary of meta-analyses.

Risk factor Blood transfusion Tumour Obesity Diabetes Tobacco use
Case number RF+SSI+ 39 226 720 229 340
RF+SSI− 998 3924 28 717 5330 13 645
RF− SSI+ 1075 769 531 1314 938
RF− SSI− 62 830 44 733 36 398 62 893 54 500
Meta-analysis LogOR 0.94 0.8 0.58 0.53 0.36
OR 2.55 2.23 1.79 1.7 1.43
SE 0.17 0.09 0.12 0.15 0.07
z 5.57 8.8 5.07 3.5 5.54
P value <0.001 <0.001 <0.001 <0.001 <0.001
Heterogeneity test I2 0.00% 0.00% 67.56% 64.07% 0.00%
Q (df) 0.17 (3) 1.34 (4) 11.58 (4) 21.13 (7) 5.78 (5)
P value 0.983 0.85 0.02 <0.001 0.33
Leave-one-out sensitivity lowest LogOR 0.88 0.7 0.54 0.44 0.32
Highest LogOR 0.96 0.86 0.66 0.64 0.43
Egger’s publication bias β 0.09 0.05 1.79 −1.21 0.76
SE 1.08 0.81 7.6 0.89 0.73
z 0.08 0.06 1.12 −1.35 0.91
P value 0.934 0.95 0.263 0.178 0.363

The presenting data of the tumour were after exclusions of outliers.

I² refers, Heterogeneity index; RF+, exposure to the risk factor; RF−, no exposure to the risk factor; SSI, surgical site infections; SSI+, SSI positive; SSI−, SSI negative.