Table 1. Background variables and clinical phenotypes of patients included in the regional SLE cohort.
| All patients(n=351) | SLE without psoriasis(n=339) | SLE with psoriasis(n=12) | P value | |
|---|---|---|---|---|
| Variables * | ||||
| Female sex, n (%) | 302 (86.0) | 296 (87.3) | 6 (50.0) | 0.003 |
| Age at SLE diagnosis (years), median (IQR) | 38.0 (26.0–53.0) | 37.0 (26.0–53.0) | 42.5 (34.0–61.0) | 0.3 |
| Caucasian origin, n (%) | 305 (86.9) | 294 (86.7) | 11 (91.7) | 1.0 |
| Number of fulfilled 1982 ACR criteria, mean (SD) | 4.8 (1.3) | 4.8 (1.3) | 5.0 (1.4) | 0.7 |
| Disease duration (years), median (IQR) | 16.0 (8.0–25.0) | 16.0 (8.0–25.0) | 20.0 (10.5–23.8) | 0.7 |
| Ever smoker, n (%) | 163 (46.4) | 154 (45.4) | 9 (75.0) | 0.07 |
| BMI (kg/m2), median (IQR) | 25.8 (8.0–25.0) | 25.8 (8.0–25.0) | 25.6 (10.5–23.8) | 0.9 |
| Clinical phenotypes* (fulfilled 1982 ACR criteria), n (%) | ||||
| Malar rash | 134 (38.2) | 130 (38.3) | 4 (33.3) | 1.0 |
| Discoid lupus | 54 (15.4) | 51 (15.0) | 3 (25.0) | 0.4 |
| Photosensitivity | 182 (51.9) | 173 (51.0) | 9 (75.0) | 0.1 |
| Oral ulcers | 45 (12.8) | 45 (13.3) | 0 (0.0) | 0.4 |
| Arthritis | 270 (76.9) | 259 (76.4) | 11 (91.7) | 0.3 |
| Serositis | 123 (35.0) | 119 (35.1) | 4 (33.3) | 1.0 |
| Renal disorder | 93 (26.5) | 89 (26.3) | 4 (33.3) | 0.5 |
| Neurological disorder | 20 (5.7) | 19 (5.6) | 1 (8.3) | 0.5 |
| Haematological disorder | 219 (62.4) | 212 (62.5) | 7 (58.3) | 0.8 |
| Immunological disorder | 200 (57.0) | 195 (57.5) | 5 (41.7) | 0.4 |
| ANA† | 347 (98.9) | 335 (98.8) | 12 (100.0) | 1.0 |
*
Data from last available visit.
†
Immunofluorescence microscopy.
ACR, American College of Rheumatology; BMI, body mass index.