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. 2025 May 16;49:fuaf020. doi: 10.1093/femsre/fuaf020

Table 3.

Bacterial membrane transporters responsible for the transport of osmoprotectants.

Transport system Osmoprotectants Microorganism References
EctP Betaine, ectoine, and proline Corynebacterium glutamicum Wood et al. (2001)
BetP Betaine and glycine Corynebacterium glutamicum Wood et al. (2001)
BetT Betaine, carnitine, and choline Haemophilus influenzae, Pseudomonas syringae Chen and Beattie (2008)
BetU Betaine, carnitine, and choline E. coli Ly et al. (2004)
BetS Glycine betaine/proline S. meliloti Boscari et al. (2002)
BCCT Betaine, carnitine, and choline Vibrio parahaemolyticus Ongagna-Yhombi et al. (2015)
BusA and QacT Dimethylsulfoniopropionate, carnitine, and proline Pediococcus pentosaceus, Tetragenococcus halophila Baliarda et al. (2003)
Cbc Betaine, carnitine, and choline Pseudomonas aeruginosa PA14 Chen et al. (2010)
GabP Proline B. subtilis Zaprasis et al. (2014)
GltT Glutamate B. subtilis Zhu and Stülke (2018)
GgtB Glucosylglycerol, sucrose, and trehalose Synechocystis sp. PCC6803 Mikkat and Hagemann (2000)
OpuA Dimethyl sulfoacetate, GB, homobetaine, and proline–betaine Bacillsus subtilis, Lactococcus lactis Wood et al. (2001), Hoffmann and Bremer (2011), Hoffmann and Bremer (2017)
OpuB Choline Bacillsus subtilis Jebbar et al. (1997), Hoffmann and Bremer (2011), Hoffmann and Bremer (2017)
OpuC Carnitine, choline, choline-o-sulfate, crotonobetaine, dimethyl sulfoacetate, ectoine, gamma-butyrobetaine, GB, homobetaine, and proline–betaine Bacillsus subtilis, Pseudomonas syringae Jebbar et al. (1997), Chen and Beattie (2007), Hoffmann and Bremer (2011), Hoffmann and Bremer (2017)
OpuD Dimethyl sulfoacetate, GB, and proline Bacillsus subtilis Wood (2007), Hahne et al. (2010), Hoffmann and Bremer (2017)
OpuE Proline Bacillsus subtilis Hoffmann and Bremer (2011), Hoffmann and Bremer (2017)
Porter II Carnitine and GB Listeria monocyogenes Wood et al. (2001)
Prop and ProU Glycine betaine, pipecolic acid, and proline–betaine E. coli, Corynebacterium glutamicum Gouesbet et al. (1992), Haardt et al. (1995), Wood et al. (2001)
PutPA Proline E. coli Wood (2007)
TeaABC Ectoine and hydroxyectoine Halomonas elongata Tetsch and Kunte (2002), Kuhlmann et al. (2008)
QacT Proline and quaternary ammonium osmoprotectant Lactobacillus plantarum Wood et al. (2001)