Table 1.
Description of study population
| Characteristic | Total Cohort (N = 120) |
|---|---|
| Age, years, mean (SD) | 70.4 (13.7) |
| Sex | |
| Female | 52 (43.3%) |
| Male | 68 (56.7%) |
| Race | |
| Asian | 10 (8.3%) |
| Black or African American | 35 (29.2%) |
| White | 27 (22.5%) |
| Unknown/Not reported | 48 (40.0%) |
| Elixhauser comorbidity indexa | 0 [0–5] |
| Elixhauser comorbidities | |
| AIDS/HIV | 2 (2.5%) |
| Alcohol abuse | 1 (1.3%) |
| Cardiac arrhythmia | 12 (15.0%) |
| Congestive heart failure | 12 (15.0%) |
| Chronic pulmonary disease | 8 (10.0%) |
| Depression | 3 (3.8%) |
| Drug abuse | 1 (1.3%) |
| Fluid and electrolyte disorders | 1 (1.3%) |
| Hypothyroidism | 7 (8.8%) |
| Hypertension, uncomplicated | 47 (58.8%) |
| Liver disease | 2 (2.5%) |
| Metastatic cancer | 1 (1.3%) |
| Obesity | 2 (2.5%) |
| Other neurological disorders | 4 (5.0%) |
| Pulmonary circulation disorders | 1 (1.3%) |
| Psychoses | 1 (1.3%) |
| Peripheral vascular disorders | 2 (2.5%) |
| Renal failure | 5 (6.3%) |
| Rheumatoid arthritis/collagen vascular disease | 1 (1.3%) |
| Solid tumor without metastasis | 7 (8.8%) |
| Valvular disease | 3 (3.8%) |
| Occlusion location | |
| Intracranial or extracranial internal carotid artery | 18 (15.0%) |
| Anterior cerebral artery | 3 (2.5%) |
| Middle cerebral artery | 88 (73.3%) |
| Vertebral artery or top of basilar artery | 2 (1.7%) |
| Posterior cerebral artery | 9 (7.5%) |
| Initial NIH stroke scaleb | 12 [6–20] |
| Time between CTP and last known well, hours | 13.7 [8.9–23.2] |
| Time between initial neuroimaging and CTP, minutes | 22.7 [16.8–29.9)] |
| Mechanical thrombectomy | |
| Yes | 75 (62.5%) |
| No | 45 (37.5%) |
| Penumbra volume (Tmax > 6 s), cc | 91.5 [40.8–164.5] |
| Core volume (CBF < 30%), cc | 7.4 [0.0–30.3] |
| Penumbra-to-core ratio | |
| P:C > = 1.8 | 106 (88.3%) |
| P:C < 1.8 | 14 (11.7%) |
SD standard deviation, NIH National Institutes of Health, CTP computed tomographic perfusion of brain, CTH computed tomography of head without contrast, Tmax time to maximal contrast density, CBF cerebral blood flow, cc cubic centimeters.
Note: Categorical variables are reported as n (%); continuous variables are reported as median [IQR] unless otherwise specified.
aElixhauser comorbidity index was collected for 80 (66.7%) patients.
b Initial NIH stroke scale which was collected for 113 (94.2%) patients.