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. 2025 Jun 6;15:19958. doi: 10.1038/s41598-025-05633-6

Table 2.

POCT and laboratory parameters of patient’s divided in two subgroups according pH-A. Student’s t-test for independent variables, *chi quadrat test. Abbreviations: SD, standard deviations; BMI, body mass index; pO2, oxygen partial pressure; pCO2, carbon dioxide partial pressure; HCO3, bicarbonate; BE, base excess; K+, potassium; Na+, sodium; Ca2+, ionized calcium; Cl, chloride; AG, uncorrected anion gap; Pi, phosphate; PTH, parathormone; eGFR, estimated glomerular filtration rate. *The index deltaAG/deltaHCO3 includes AG corrected to potassium and albumin.

POCT and laboratory parameters
pH-A ≤ 7.33 N = 52 pH-A > 7.33 N = 63 p All study patients N = 115
pH-A 7.28 ± 0.04 7.38 ± 0.03 < 0.01 7.33 ± 0.06
pCO2-A (mmHg) 32.91 ± 4.9 35.72 ± 4.72 < 0.01 34.45 ± 4.98
pO2-A (mmHg) 88.34 ± 17.05 83.42 ± 15.5 > 0.05 85.65 ± 16.33
HCO3-A (mmol/l) 15.53 ± 2.76 20.95 ± 3.08 < 0.01 18.50 ± 3.99
BE-A (mmol/l) (−10.22 ± 2.81) (−3.66 ± 2.91) < 0.01 (−6.63 ± 4.34
K+-A (mmol/l) 4.60 ± 0.71 4.26 ± 0.81 < 0.05 4.41 ± 0.78
Na+-A (mmol/l) 141.29 ± 2.44 139.97 ± 3.57 < 0.05 140.57 ± 3.17
Cl-A (mmol/l) 115.98 ± 4.03 109.29 ± 4.77 < 0.01 112.31 ± 5.55
AG-A (mmol/l) 9.86 ± 2.35 9.72 ± 2.33 > 0.05 9.78 ± 2.33
Cl/HCO3-A (mmol/l)/(mmol/l) 7.76 ± 1.7 5.36 ± 0.99 < 0.01 6.44 ± 1.81
deltaAG/deltaHCO3 * 1.52 ± 1.36 −0.4 ± 5.3 < 0.05 0.47 ± 4.13
pH-V 7.24 ± 0.07 7.31 ± 0.06 < 0.01 7.28 ± 0.07
pCO2-V (mmHg) 35.25 ± 4.99 38.57 ± 4.6 < 0.01 37.07 ± 5.04
pO2-V (mmHg) 63.50 ± 15.27 58.12 ± 11 < 0.05 60.53 ± 13.3
HCO3-V (mmol/l) 15.09 ± 3.01 19.71 ± 3.54 < 0.01 17.62 ± 4.02
BE-V (mmol/l) −11.44 ± 3.58 −6.03 ± 4.01 < 0.01 −8.48 ± 4.67
K+-V (mmol/l) 4.67 ± 0.71 4.31 ± 0.75 < 0.05 4.47 ± 0.75
Na+-V (mmol/l) 141.54 ± 2.6 140.67 ± 3.31 > 0.05 141.06 ± 3.03
Cl-V (mmol/l) 115.85 ± 3.93 109.46 ± 4.7 < 0.01 112.35 ± 5.4
AG-V (mmol/l) 10.81 ± 2.67 11.47 ± 2.3 > 0.05 11.17 ± 2.49
Cl/HCO3-V (mmol/l)/(mmol/l) 8.05 ± 2.02 5.77 ± 1.26 < 0.01 6.80 ± 2.0
ΔHCO3 (mmol/l) 0.89 ± 1.7 1.95 ± 1.79 < 0.01 1.47 ± 1.82
Total protein (g/dl) 5.75 ± 0.78 6.12 ± 1.01 < 0.05 5.96 ± 0.93
Pi (mg/dl) 5.90 ± 1.29 5.13 ± 1.15 < 0.01 5.48 ± 1.27
PTH (pg/ml) 424.28 ± 262.27 294.3 ± 185.8 < 0.01 350.01 ± 229.76
Hemoglobin (g/dl) 9.63 ± 1.33 10.33 ± 1.5 < 0.01 10.02 ± 1.46
Creatinine (mg/dl) 5.58 ± 1.68 5.23 ± 1.95 > 0.05 5.39 ± 1.83
eGFR (ml/min/1.73 m2) 10.45 ± 3.06 12.69 ± 4.8 < 0.01 11.68 ± 4.24
Urea (mg/dl) 152.66 ± 31.62 141.74 ± 43.08 > 0.05 146.68 ± 38.55