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. 2025 May 14;4(6):101786. doi: 10.1016/j.jacadv.2025.101786

Table 3.

Secondary Outcomes by Sex

Outcomes Sex Pooled Effect Sizes
1,500-3,000 MET-min/wk
>3,000 MET-min/wk
No. of Studies Mean Difference (95% CI) Heterogeneity (I2, P Value) No. of Studies Mean Difference (95% CI) Heterogeneity (I2, P Value)
No. of calcified plaques per patients Males 2 −0.03 (−0.87 to 0.81, P = 0.95) (94.87%, P < 0.001) 2 0.82 (−0.14 to 1.78, P = 0.09) (92.45%, P < 0.001)
Females 2 −0.24 (−0.51 to 0.04, P = 0.09) (85.63%, P < 0.001) 2 −0.26 (−0.42 to −0.1, P < 0.001) (0%, P = 0.28)
Calcified lesions volume Males 1 −16.23 (−27.56 to −4.9, P < 0.001) 2 26.91 (12.06-41.76, P < 0.001) (0%, P = 0.32)
Females 1 −10.75 (−16.52 to −4.98, P < 0.001) 2 −16.89 (−38.17 to 4.39, P = 0.12) (29.18%, P = 0.16)
Calcified plaques Males 1 OR 1.52 (0.96-2.42, P = 0.07) 2 OR 2.31 (0.67-7.98, P = 0.19) (87.42%, P < 0.001)
Females

Abbreviations as in Table 1.