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. 2025 May 14;14:102050. doi: 10.1016/j.toxrep.2025.102050

Table 6.

Toxicity analysis of toxic heavy metals in S. cocculoides.

Tested toxicities Toxic Heavy Metals
Al Cd Cr Ni
Predicted LD50 (mg/kg) 5000 890 440 780
Predicted toxicity class 5 4 3 4
Hepatotoxicity (prediction/ probability) I/0.97 I/0.98 I/0.98 I/0.97
Neurotoxicity
(prediction/ probability)
A/0.59 A/0.59 A/0.59 A/0.59
Nephrotoxicity
(prediction/ probability)
A/0.84 I/0.84 I/0.84 I/0.84
Respiratory toxicity
(prediction/ probability)
A/0.77 I/0.77 I/0.77 A/0.77
Cardiotoxicity
(prediction/probability)
I/0.98 I/0.99 I/0.92 I/0.98
Carcinogenicity (prediction/ probability) I/0.69 I/0.62 I/0.65 I/0.83
Immunotoxicity (prediction/probability) I/0.99 A/0.99 I/0.99 A/0.99
Mutagenicity (prediction/ probability) I/0.75 I/0.76 I/0.76 I/0.76
Cytotoxicity (prediction/ probability) I/0.74 I/0.79 I/0.79 I/0.79
BBB-Barrier A/1.0 A/1.0 A/1.0 A/1.0
Ecotoxicity A/0.85 A/0.85 A/0.85 A/0.85
Clinical toxicity
(prediction/ probability)
I/0.83 I/0.84 I/0.84 I/0.84