Table 10. List of various mitochondrial microRNA therapeutics, undergoing clinical trials.
| Therapeutic molecule | Associated mitomiR | Cancer | Stage of clinical trials |
|---|---|---|---|
| MRG-106 | miR-155 | Blood cancer | Phase I |
| MRG-201 | miR-29b | Blood cancer fibrosis | Phase II |
| Cetuximab/FOLFOX | miR-31-3p, miR-31-5p | Colorectal cancer | Phase III |
| interferon-alpha (IFN alpha) | miR-26 | Hepatocellular carcinoma | Phase III |
| Miravirsen | miR-122 | Hepatocellular carcinoma | Phase II |
| RG-101 | miR-122 | Hepatocellular carcinoma | On hold |
| MRX-34 | miR-34 | Advanced Solid Tumor | Phase I |
| MRG-110 | miR-92a | Angiogenesis | Phase I completed |
Note: *Adapted from [134] and modified.