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. 2025 May 29;33(6):1301–1321. doi: 10.32604/or.2025.055945

Table 2. Localized/Enriched mitochondrial miRNAs and their functions.

Sr. No. MiRNAs Functions References
1 miR-494 Affects ATP synthesis and leads to mitochondrial dysfunction [124]
2. miR-132 Inhibits complex 1 of mitochondria and reduces aerobic respiration [125]
3. miR-34a Synaptic plasticity dysfunction [126]
4. miR-365 Accumulation of ECM components and secretion of inflammatory cytokines [127]
5. miR-338 Reduces mitochondrial oxygen consumption [128]
6. miR-484 Inhibits mitochondrial fission [129]
7. miR-218 Inhibits mitophagy and mitochondrial clearance [129]
8. miR-212 Enhance neurotransmission and be involved in synaptic plasticity [125]
9. miR-146a Induces inflammatory response and contributes to cell aging [130]
10. miR-130a Induced neurotoxicity and cell apoptosis [124]
11. miR-130b Inhibits cell proliferation and induces cell apoptosis [124]
12. miR-140 Inhibits mitochondria dysfunction and enhances autophagy [124]