Table 2.
NASPA, ELLA and ELISA titers of MAbs against type B NA (NB), N1 and N2
| Assay Virus | MAb | ELISA titera | ELLA titerb | NASPA titerc |
|---|---|---|---|---|
| NB/Austria21 Virus | 6G1-1 | 640 | 1315 | 540 |
| 22B10-1 | >1280 | 2055 | 540 | |
| 11D1-1 | 640 | 925 | −180* | |
| 12H3-1 | 320 | 310 | 180 | |
| 16H10-1 | 640 | 1080 | −180* | |
| 5A4-1 | 320 | 490 | 60 | |
| 41H4-1 | 160 | 830 | 60 | |
| 45B3-1 | 320 | 280 | 20 | |
| 48G11-1 | 320 | 125 | 20 | |
| 58F4-1 | 80 | 40 | 20 | |
| 33H3-1 | 80 | 35 | −20* | |
| 2G10-1 | 320 | 50 | <20* | |
| 31H2-1 | 80 | 55 | <20 | |
| 6D4-1 | 160 | 35 | <20 | |
| 32B4-1 | 80 | <20 | <20 | |
| 54D7-1 | 40 | <20 | <20 | |
| 57F12-1 | 40 | <20 | <20 | |
| N1/Vic19 Virus | 9F12-1 | 512 | 3380 | 1280 |
| 17D7-1 | 128 | 1870 | 1280 | |
| 7G6-2 | 512 | <20 | <20 | |
| 17G5-2 | 512 | <20 | <20 | |
| 5D11-1 | 128 | <20 | <20 | |
| N2/Dar21 virus | 7H10-2 | 160 | 675 | 320** |
| 3D9-1 | 640 | 960 | 160* | |
| 14B10-2 | 320 | 745 | 80* | |
| 13F10-2 | >1280 | <20 | <20* | |
| 10F12-1 | 320 | <20 | <20 |
aEnd point titers correspond to the lowest dilution 2-fold above the control (Supplementary Fig. 8a–c).
bELLA titers correspond to the IC50 (Supplementary Fig. 8d–f).
cNASPA titers are the highest dilution factor above or below (negative values) the mean control ±3 SD.
Displayed enzymatic (*) inhibition or (**) activation with MUNANA (Supplementary Fig. 9).