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Relative gene-targeting efficiencies of diverged repair substrates. The frequency of neo+ colonies was plotted for the cotransfections of each of the pneo substrates with pPGK3xnlsI-SceI relative to the pneo-WT with pPGK3xnlsI-SceI control. In each case, the mean of five independent experiments is shown with the standard deviation indicated by an error bar.
