Table 13:
Change in Acute Medication Use, nVNS vs. Standard of Care, Prevention, Cluster Headache
| Author, year (study) | Participants, nVNS/control, n | Measure | Mean change from baseline (95% CI)a | Mean difference (95% CI) | |
|---|---|---|---|---|---|
| nVNS | Control | ||||
| Gaul et al, 201653 (PREVA) | 32/42 | Overall | -15 (-22.8 to -7.2) | -2 (-9.4 to 5.4) | -13 (-23.38 to -2.62)b |
| Subcutaneous sumatriptan | -4.4 (-7.6 to -1.2) | 0.7 (NR) | -5.1 (NR) | ||
| Inhaled oxygen | -10.8 (-19.4 to -2.2) | -1.8 (NR) | -9 (NR) | ||
Abbreviations: CI, confidence interval; NR, not reported; nVNS, noninvasive vagus nerve stimulation.
a
Number of times that acute medication was used during the last 2 weeks of randomization.
b
Calculated from data provided in study.