Table 30:
Quality of Life, nVNS vs. Control, Prevention, Migraine
| Author, year (study) | Measure | Participants, nVNS/standard of care, n | Quality of life, mean (SD) or % | Change score | P | |
|---|---|---|---|---|---|---|
| nVNS | Control | |||||
| Chaudhry et al, 201959 | MIDAS | 14/12 | Baseline: 3.86 (0.1) Follow-up: 3.57 (0.25) |
Baseline: 3.92 (0.08) Follow-up: 3.83 (0.11) |
Mean difference: -0.2 (NR) | .24 |
| Najib et al, 202258 (PREMIUM II) | HIT-6 | 54/54 | Change from baseline: -4.9 (NR) | Change from baseline: -2.3 (NR) | Mean difference: -2.6 (NR) | .025 |
| MIDAS | 44/44 | 25% | 9.10% | Absolute difference: 15.9% | .047 | |
Abbreviations: CI, confidence interval; MIDAS, Migraine Disability Assessment; HIT-6, Headache Impact Test-6; NR, not reported; nVNS, noninvasive vagus nerve stimulation.