Table 34:
Clinical Parameters Used in the Economic Model, Cluster Headache
| Clinical parameter | Meana | Distribution | Reference |
|---|---|---|---|
| Number of cluster headache attacks per 4 weeks at baseline | 67.3 (SE 6.3) | Normal | Gaul et al, 201653 (PREVA); clinical evidence review, Table 2 |
| Change from baseline in number of cluster headache attacks per week with nVNS | -3.9 (95% CI -7.2 to -0.52) | Normal | Gaul et al, 201653 (PREVA); clinical evidence review, Table 11 |
| Reduction in subcutaneous sumatriptan use | 61% | Beta | Gaul et al, 201653 (PREVA) |
| Reduction in inhaled oxygen use (societal perspective only) | 62% | Beta | Gaul et al, 201653 (PREVA) |
Abbreviations: CI, confidence interval; nVNS; noninvasive vagus nerve stimulation; SE, standard error.
a
For distributions where the 95% CI was not reported, we assumed that the SE was 15% of the mean.