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. 2025 May 1;25(2):1–177.

Table 37:

Costs of Monitoring, Medication, and Productivity Loss, Cluster Headache

Cost Cost per 4 wk, Ministry of Health perspective Cost per 4 wk, societal perspective Distribution Reference
Monitoring: neurologist or headache specialist visit and ECG for verapamil use $14.18 $25.95 Normal Schedule of Benefits (A185 + G310, G313)96
Acute medication: sumatriptan succinate injection $132.27 $549.00 Normal Ontario Drug Benefit formulary for unit costs99; frequency based on NICE medical technologies guidance30
Acute medication: inhaled oxygen (societal perspective only, scenario analysis) $0.00 $608.15 Normal O’Brien et al, 2017100
Preventive medication: verapamil $46.16 $192.00 Normal Ontario Drug Beneft formulary for unit costs99; frequency based on treatment guidelines12 (80 to 240 mg BID)
Productivity loss (societal perspective only, scenario analysis) $0 $653.75 Normal (hourly wage) Calculated based on Ford et al, 2018,101 and average hourly wage in Ontario102

Abbreviation: BID, twice a day.

All costs are expressed in 2023 CAD. All parameters were modelled as fixed (i.e., no assigned distributions).

Abbreviations: ECG, electrocardiogram; NICE, National Institute for Health and Care Excellence.