Table 39:

Utilities Used in the Economic Model, Migraine

Parameter	Mean EQ-5D index score (95% CI) or %	Distribution	Reference
Pain-free	0.87 (0.84 to 0.9)	Beta	Stafford et al, 2012106
Mild pain	0.66 (0.62 to 0.71)	Beta	Stafford et al, 2012106
Moderate pain	0.53 (0.47 to 0.59)	Beta	Stafford et al, 2012106
Severe pain	-0.20 (-0.27 to -0.13)	Beta	Stafford et al, 2012106
Proportion with severe migraine	20%	Dirichlet	Tassorelli et al, 201784 (PRESTO); weighted average from nVNS and sham arms
Proportion with moderate migraine	44%	Dirichlet	Tassorelli et al, 201784 (PRESTO); weighted average from nVNS and sham arms
Proportion with mild migraine	36%	Dirichlet	Tassorelli et al, 201784 (PRESTO); weighted average from nVNS and sham arms

Abbreviations: CI, confidence interval; nVNS, noninvasive vagus nerve stimulation.