Table 40:
Monthly Costs of Monitoring, Medications, and Productivity Loss, Migraine
| Migraine cost | Cost per month, Ministry of Health perspective | Cost per month, societal perspective | Reference |
|---|---|---|---|
| Monitoring: neurologist or headache specialist visit | $15.37 | $28.12 | Schedule of Benefits (A185)96 |
| Medication (acute) | |||
| Triptans | |||
| Sumatriptan (all modalities) | $34.05 | $141.28 | Amoozegar et al, 202291 |
| Almotriptan | $18.59 | $77.12 | Amoozegar et al, 202291 |
| Rizatriptan | $22.93 | $95.14 | Amoozegar et al, 202291 |
| Eletriptana | $0.00 | $123.72 | Amoozegar et al, 202291 |
| Frovatriptana | $0.00 | $107.31 | Amoozegar et al, 202291 |
| Naratriptan | $22.93 | $95.14 | Amoozegar et al, 202291 |
| Zolmtriptan | $8.18 | $33.94 | Amoozegar et al, 202291 |
| Ergots | |||
| Dihydroergotaminea | $0.00 | $14.98 | Amoozegar et al, 202291 |
| Metoclopramide | $0.01 | $0.02 | Amoozegar et al, 202291 |
| Ondansetron hydrochloride | $2.89 | $12.01 | Amoozegar et al, 202291 |
| Opioids | |||
| Analgesics with opioids or barbiturates | $0.56 | $2.33 | Amoozegar et al, 202291 |
| Medication (prevention) | |||
| Antihypertensives | |||
| Propranolol (40 mg × 2 per d) | $0.90 | $3.72 | Amoozegar et al, 202291 |
| Nadolol (40 mg) | $3.50 | $14.54 | Amoozegar et al, 202291 |
| Metoprolol | $0.93 | $3.85 | Amoozegar et al, 202291 |
| Antidepressants | |||
| Amitriptyline (10 mg) | $0.50 | $2.07 | Amoozegar et al, 202291 |
| Nortitriptylinea | $0.00 | $6.89 | Amoozegar et al, 202291 |
| Venlafaxine | $0.74 | $3.08 | Amoozegar et al, 202291 |
| Antiepileptics | |||
| Divalproex dosium/valproic acid | $1.87 | $7.75 | Amoozegar et al, 202291 |
| Gabapentin | $10.15 | $42.11 | Amoozegar et al, 202291 |
| Topiramate | $3.17 | $13.15 | Amoozegar et al, 202291 |
| Calcium channel blockers | |||
| Flunarizine | $1.68 | $6.98 | Amoozegar et al, 202291 |
| Serotonin antagonists | |||
| Pizotifen | $58.24 | $241.66 | Amoozegar et al, 202291 |
| Other | |||
| Erenumab | $42.59 | $176.71 | Amoozegar et al, 202291 |
| Naproxen sodiuma | $0.00 | $3.42 | Amoozegar et al, 202291 |
| Diclofenac powder for oral solutiona | $0.00 | $5.89 | Amoozegar et al, 202291 |
| Onabotulinum toxin A (botox) | $58.24 | $241.66 | Amoozegar et al, 202291 |
| Productivity loss (societal perspective only, scenario analysis) | $0 | $351.20 | Calculated based on Lambert et al107 and average hourly wage in Ontario102 |
All costs are expressed in 2023 CAD. Medications for which the Ministry of Health costs are $0 indicate that a provincial drug program does not cover the medication. Costs were inflated from 2018 CAD to 2022 CAD in the study by Amoozegar et al.91 All parameters were modelled as fixed (i.e., no assigned distributions).
a
This medication is not available for coverage through a public provincial drug program.