Table 42a:
Reference Case Analysis, Disaggregated Results, Cluster Headache
| Outcome | nVNS in addition to standard care, mean (95% CrI) | Standard care alone, mean (95%CrI) | Mean difference (95% CrI)a,b |
|---|---|---|---|
| Cost outcomes | |||
| Total cost per person per year | $7,833 ($7,549 to $8,267) | $2,516 ($1,975 to $3,070) | $5,317 ($4,859 to $5,728) |
| Cost of nVNS | $6,369 | $0 | $6,369 |
| Cost of acute medication | $668 | $1,720 | -$1,052 |
| Cost of preventive medication | $599 | $599 | $0 |
| Cost of monitoring | $1,116 | $1,116 | $0 |
| Effectiveness outcomes | |||
| Number of attacks per year | 671 (433 to 908) | 872 (712 to 1,030) | -201 (-378 to -21) |
| Total QALYs | 0.6941 (0.4642 to 0.8931) | 0.4996 (0.3140 to 0.6411) | 0.1945 (0.0461 to 0.3276) |
Abbreviations: Crl, credible interval; ICER, incremental cost-effectiveness ratio; nVNS; noninvasive vagus nerve stimulation; QALY, quality-adjusted life-year.
a
Results may appear inexact due to rounding.
b
Negative costs indicate savings.