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. 2025 May 1;25(2):1–177.

Table 55:

Budget Impact Analysis Results, nVNS for Prevention, Cluster Headache

Scenario Budget impact, $ milliona
Year 1 Year 2 Year 3 Year 4 Year 5 Totalb,c
Current scenario 29.83 30.50 31.04 31.47 31.924 154.765
   Acute medication costs 20.40 20.83 21.23 21.52 21.83 105.83
   Prevention medication costs 7.11 7.27 7.40 7.50 7.60 36.90
   Monitoring costs 2.32 2.37 2.41 2.45 2.482 12.03
New scenario
   Standard care alone 29.53 29.89 30.11 30.21 30.27 150.07
      Acute medication costs 20.19 20.46 20.59 20.66 20.74 102.62
      Preventive medication costs 7.04 7.13 7.18 7.20 7.23 35.78
      Monitoring costs 2.30 2.32 2.34 2.35 2.36 66.57
   nVNS + standard care 0.93 1.90 2.90 3.92 4.97 14.62
      nVNS costs 0.76 1.54 2.36 3.19 4.04 11.88
      Acute medication costs 0.079 0.16 0.25 0.33 0.42 1.24
      Preventive medication costs 0.071 0.15 0.22 0.30 0.38 1.12
      Monitoring costs 0.023 0.047 0.072 0.098 0.12 0.37
Budget impactb,c 0.63 1.29 1.97 2.66 3.37 9.92
   nVNS costs 0.76 1.54 2.36 3.19 4.04 11.88
   Acute medication costs -0.12 -0.26 -0.39 -0.53 -0.67 -1.96
   Preventive medication costs 0.00 0.00 0.00 0.00 0.00 0.00
   Monitoring costs 0.00 0.00 0.00 0.00 0.00 0.00

Abbreviation: nVNS; noninvasive vagus nerve stimulation.

a

In 2024 Canadian dollars.

b

Negative costs indicate savings.

c

Results may appear inexact due to rounding.