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. 2025 May 1;25(2):1–177.

Table 56:

Scenario Analysis Results, nVNS for Acute Treatment, Cluster Headache

Analysis Budget impact, $ milliona
Year 1 Year 2 Year 3 Year 4 Year 5 Totalb
Reference case 0.76 1.54 2.36 3.19 4.04 11.88
1: nVNS provided free for the first 93 days 0.49 1.01 1.54 2.08 2.64 7.77
2: Annual uptake of 2% per year, up to 10% in year 5 1.51 3.09 4.72 6.37 8.08 23.77
3: Annual uptake of 20% per year, up to 100% in year 5 15.1 30.88 47.15 63.74 80.81 237.69
4a: Cost of the nVNS device decreased by 25% 0.57 1.15 1.76 2.39 3.03 8.91
4b: Cost of the nVNS device increased by 25% 0.94 1.93 2.94 3.98 5.05 14.86

Abbreviation: nVNS, noninvasive vagus nerve stimulation.

a

In 2024 Canadian dollars.

b

Results may appear inexact due to rounding.