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. 2025 May 1;25(2):1–177.

Table 57:

Scenario Analysis Results, nVNS for Prevention, Cluster Headache

Scenario Budget impact, $ milliona
Year 1 Year 2 Year 3 Year 4 Year 5 Totalb
Reference case 0.63 1.29 1.97 2.66 3.37 9.92
1: nVNS provided free for the first 93 days 0.37 0.76 1.15 1.56 1.98 5.82
2: Annual uptake of 2% per year, up to 10% in year 5 1.26 2.58 3.94 5.32 6.75 19.84
3: Annual uptake of 20% per year, up to 100% in year 5 12.61 25.78 39.36 53.21 67.47 198.43
4a: Cost of the nVNS device decreased by 25% 0.44 0.91 1.38 1.87 2.37 6.97
4b: Cost of the nVNS device increased by 25% 0.82 1.68 2.56 3.46 4.38 12.89

Abbreviation: nVNS, noninvasive vagus nerve stimulation.

a

In 2024 Canadian dollars.

b

Results may appear inexact due to rounding.