Table 59:

Budget Impact Analysis Results, nVNS for Prevention, Migraine

Scenario	Budget impact, $ milliona
	Year 1	Year 2	Year 3	Year 4	Year 5	Totalb,c
Current scenario	807.66	824.9	838.84	849.9	861.45	4,182.75
Acute medication costs	141.45	144.47	146.91	148.84	150.87	732.54
Prevention medication costs	614.47	627.59	638.19	646.61	655.4	3,182.27
Monitoring costs	51.74	52.84	53.74	54.44	55.18	267.95
New scenario
Standard care alone	799.58	808.41	813.67	815.9	818.38	4,055.94
Acute medication costs	140.03	141.58	142.5	142.89	143.33	710.33
Preventive medication costs	608.33	615.04	619.05	620.74	622.63	3,085.79
Monitoring costs	51.22	51.79	52.12	52.27	52.43	259.82
nVNS + standard care	25.83	52.77	80.49	108.73	137.76	405.58
nVNS costs	17.89	36.54	55.74	75.3	95.41	280.88
Acute medication costs	1.28	2.61	3.99	5.39	6.83	20.1
Preventive medication costs	6.14	12.55	19.15	25.86	32.77	96.48
Monitoring costs	0.52	1.06	1.61	2.18	2.76	8.12
Budget impactb,c	17.76	36.27	55.32	74.74	94.69	278.77
nVNS costs	17.89	36.54	55.74	75.3	95.41	280.88
Acute medication costs	-0.13	-0.27	-0.42	-0.57	-0.72	-2.11
Preventive medication costs	0.00	0.00	0.00	0.00	0.00	0.00
Monitoring costs	0.00	0.00	0.00	0.00	0.00	0.00

Abbreviation: nVNS, noninvasive vagus nerve stimulation.

^aIn 2024 Canadian dollars.

^bNegative costs indicate savings.

^cResults may appear inexact due to rounding.