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. 2025 May 1;25(2):1–177.

Table A10:

Proportion of All Attacks Achieving Pain Relief, nVNS vs. Control, Acute Treatment, Migraine

Author, year (study) Time, min Total attacks, nVNS/control, n Percent (95% CI) P a
nVNS Control
Martelletti et al, 201864 (PRESTO) 120 373/347 35.2 (28.9-42.2) 24.4 (18.8-31.0) .018
60 29.4 (23.9-35.7) 20.3 (15.4-26.4) .025
30 21.4 (16.2-27.8) 16 (11.5-21.7) .15

Abbreviations: CI, confidence interval; nVNS, noninvasive vagus nerve stimulation.

a

Adjusted for pain score at baseline, use of preventive therapies, and presence of aura.