Table 23:

Budget Impact Analysis Results - Scenario Analyses

Scenario	Budget impact, $a						%changec	Total number of surgically treated patients in new scenario
	Year 1	Year 2	Year 3	Year 4	Year 5	Totalb
Reference case	251,601	311,243	371,552	432,529	494,174	1,861,100	-	110
Scenario 1, population of interest	745,359	772,804	781,482	809,150	837,041	3,945,836	112%	217
Scenario 2, increased expansion of MRgFUS neurosurgery	251,601	350,710	432,685	536,026	622,232	2,193,253	18%	126
Scenario 3, steady but slower expansion of MRgFUS neurosurgery	251,601	252,042	250,254	246,236	239,990	1,240,123	-33%	80
Scenario 4, steady but increased expansion of MRgFUS neurosurgery	488,405	500,432	510,231	517,800	523,140	2,540,008	36%	140
Scenario 5, decreased Gamma Knife radiosurgery	262,086	321,728	382,037	443,014	504,659	1,913,524	3%	110
Scenario 6, patients not eligible for MRgFUS neurosurgery receive RFA	255,472	315,114	375,423	436,401	498,045	1,880,455	1%	110
Scenario 7, public funding includes capital costs (average patient volume)	420,664	514,119	608,242	703,031	798,489	3,044,546	64%	110
Scenario 8, public funding includes capital costs (low patient volume)	437,571	534,407	631,911	730,082	828,920	3,162,890	70%	110
Scenario 9, public funding includes capital costs (high patient volume)	394,655	482,908	571,828	661,416	751,671	2,862,477	54%	110
Scenario 10, medication costs decrease by 25%	248,629	304,741	360,964	417,298	473,741	1,805,373	-3%	110
Scenario 11, 10% of patients treated with MRgFUS neurosurgery require re-treatment with Gamma Knife radiosurgery	262,226	311,243	371,552	432,529	494,174	1,871,725	1%	110
Scenario 12, 10% of patients treated with MRgFUS neurosurgery require re-treatment with RFA	269,400	311,243	371,552	432,529	494,174	1,878,899	1%	110
Scenario 13, decreased inpatient procedure cost of MRgFUS neurosurgery	217,881	270,779	324,344	378,577	433,478	1,625,058	-13%	110
Scenario 14, increased inpatient procedure cost of MRgFUS neurosurgery	285,321	351,707	418,761	486,482	554,870	2,097,141	13%	110
Scenario 15, decreased inpatient procedure cost of RFA	257,765	317,407	377,716	438,693	500,338	1,891,919	2%	110
Scenario 16, increased inpatient procedure cost of RFA	245,437	305,079	365,389	426,366	488,010	1,830,280	-2%	110
Scenario 17, decreased inpatient procedure cost of Gamma Knife radiosurgery	255,179	314,821	375,131	436,108	497,752	1,878,991	1%	110
Scenario 18, increased inpatient procedure cost of Gamma Knife radiosurgery	251,438	311,080	371,390	432,367	494,011	1,860,286	0%d	110
Scenario 19, lower estimate of RFA adverse event costs	252,178	311,820	372,129	433,106	494,751	1,863,984	0%d	110
Scenario 20, upper estimate of RFA adverse event costs	251,468	311,110	371,420	432,397	494,041	1,860,436	0%d	110
Scenario 21, lower estimate of Gamma Knife radiosurgery adverse event costs	252,740	312,382	372,691	433,669	495,313	1,866,795	0%d	110
Scenario 22, no anesthesiologist costs for MRgFUS neurosurgery	243,004	300,926	359,517	418,774	478,700	1,800,921	-3%	110
Scenario 23, alternate fee code for Gamma Knife radiosurgery	249,075	308,771	369,026	430,004	491,648	1,848,470	-1%	110
Scenario 24, public funding of DBS and replacement of DBS by MRgFUS neurosurgery	168,730	214,068	257,845	300,061	340,715	1,281,419	-31%	120
Scenario 25, increase in physician fees	253,638	313,879	374,814	436,444	498,768	1,877,543	1%	110

Abbreviations: DBS, deep brain stimulation; MRgFUS, magnetic resonance-guided focused ultrasound; RFA, radiofrequency ablation.

^aAll costs are reported in 2023 Canadian dollars.

^bResults may appear inexact due to rounding.

^cPercent change calculated as the difference in the total budget impact of the scenario analysis and the total budget impact of the reference case divided by the total budget impact of the reference case.

^dPercent change was very small (<0.5%).