Table 6:

CGI Scores Over 24-Month Follow-Up After MRgFUS Capsulotomy

Scale	CGI scores, mean (SD)
	Baseline	1 wk	1 mo	3 mo	6 mo	12 mo	24 mo	P valuea
CGI-Sb	6.1 (0.2)	5.6 (0.2)	5.4 (0.3)	4.5 (0.2)	4.4 (0.2)	4.0 (0.2)	3.9 (0.3)	.001
CGI-Ic	—	3.4 (0.2)	3.2 (0.3)	2.7 (0.2)	2.5 (0.2)	2.0 (0.3)	2.1 (0.3)	<.001

Abbreviations: CGI, Clinical Global Impression; CGI-I, Clinical Global Impression - Improvement; CGI-S, Clinical Global Impression - Severity; MRgFUS, magnetic resonance-guided focused ultrasound; SD, standard deviation.

^aAnalyzed using a linear mixed model for repeated measures across the 24-month follow-up period.

^bScores reflect the severity of mental illness the patient is experiencing at a given time (1, normal, not at all ill; 2, borderline; 3, mildly ill; 4, moderately ill; 5, markedly ill; 6, severely ill; 7, among the most extremely ill patients).⁸⁰

^cScores reflect the patient's condition relative to before the initiation of treatment (1, very much improved since treatment initiation; 2, much improved; 3, minimally improved; 4, no change; 5, minimally worse; 6, much worse; 7, very much worse).⁸⁰ Source: Kim et al.⁷⁹