Fig. 1.

Using the traditional clinical and rehabilitative practice of calculating MICDs to track progress or define treatment/intervention efficacy, we leveraged data from our previous large-scale combined ET+RT clinical trial in young individuals to generate MCIDs of exercise responsiveness. We selected an established distribution-based method to generate MCIDs based on % change from pre- to post-12 weeks of training for A) cardiorespiratory fitness (CRF) and B) functional muscle quality (fMQ). These MCID criteria generated the expected responder breakdown (‘−‘ = did not meet MCID, ‘+’ met MCID shown in the Punnet Square shown in C).