Skip to main content
. 2025 Apr 21;28(6):1199–1212. doi: 10.1038/s41593-025-01943-0

Extended Data Fig. 8. MBNL and SRRM proteins directly bind to Ank2 and regulate miE splicing.

Extended Data Fig. 8

a, Schematic of heterologous Atp2a1-Ank2 miE splicing minigenes production. MBNL (magenta) and SRRM (purple) binding sequences identified in mouse Ank2. b,c, Atp2a1-Ank2 miE splicing analysis in N2a experiments (N = 3). One-way ANOVA followed by Tukey’s multiple comparisons test; nsPadj > 0.05, **Padj < 0.01, ***Padj < 0.001, ****Padj < 0.0001. Data are presented as mean values ± SD.

Source data