Skip to main content
. 2025 Jun 9;317(1):803. doi: 10.1007/s00403-025-04301-z

Table 3.

Selected studies evaluating scarring alopecia outcomes following IL-23 inhibitor use

Author Indication Enrollment Study Drug Regimen Concurrent Therapies Outcomes
Nagshabandi et al. [32] DC 2 Risankizumab, in-clinic injection every 3 months

Patient 1: Not reported

Patient 2: Topical clindamycin 1% solution daily

At 13-month follow-up, patient 1 reported improvement of roughly 70% in scalp lesions by the fifth dose, with no new lesions or draining nodules; signs of hair growth evident

At four-month follow-up, patient 2 experienced improvements in skin lesions by the third dose

Awad et al. [33] DC 1 Tildrakizumab, two doses of subcutaneous injection given 4 weeks apart Not reported

At eight-week follow-up, the patient increased hair density and reduced the number of pustules

Patient reported alleviated scalp tenderness and hair regrowth

Trindade de Carvalho et al. [34] FFA/LPP 1 Tildrakizumab, 100 mg subcutaneously at weeks 0, 4, and subsequently 12 weekly Minoxidil 1–2 mg/day and dutasteride 0.5 mg/day

At 16-week follow-up, patient experienced symptomatic improvements

At 13-month follow-up, remission was maintained

No adverse reactions reported