Table 2.
Correlation analysis between lymphocyte subsets and cytokines in different gene mutations
| lymphocyte subsets | cytokines | P value | r value |
|---|---|---|---|
| ASXL1 | |||
| CD4 + TLs | IL-5 | 0.041 | 0.62 |
| CD4 + TLs | IL-10 | 0.009 | 0.74 |
| CD4 + TLs | IL-12p70 | 0.012 | 0.72 |
| NKTLs | IL-1β | 0.039 | 0.63 |
| RUNX1 | |||
| CD8 + TLs | IL-4 | 0.032 | -0.85 |
| CD8 + TLs | IL-5 | 0.003 | -0.96 |
| CD8 + TLs | IL-12p70 | 0.04 | -0.83 |
| NK TLs | IFN-α | 0.002 | 0.96 |
| NK TLs | IFN-γ | 0.003 | 0.96 |
| NK TLs | IL-1β | 0.001 | 0.98 |
| NK TLs | IL-2 | 0.001 | 0.97 |
| NK TLs | TNF-α | 0.043 | 0.83 |
| TBLs | IFN-α | 0.023 | -0.87 |
| TBLs | IFN-γ | 0.008 | -0.92 |
| TBLs | IL-1β | 0.012 | -0.91 |
| TBLs | IL-2 | 0.008 | -0.92 |
| Treg | IFN-α | 0.019 | 0.88 |
| Treg | IL-1β | 0.025 | 0.87 |
| Treg | IL-2 | 0.02 | 0.88 |
| Treg | TNF-α | 0.02 | 0.88 |
| SF3B1 | |||
| CD8 + TLs | IL-6 | 0.04 | 0.78 |
| TET2 | |||
| NK TLs | IL-8 | 0.012 | 0.86 |
| TP53 | |||
| CD4 + TLs | TNF-α | 0.05 | 0.88 |
| NK TLs | IL-1β | 0.049 | -0.88 |
| NK TLs | IL-4 | 0.03 | -0.91 |
| Treg | IL-2 | 0.024 | 0.93 |
| Treg | IL-4 | 0.029 | 0.92 |
| Treg | IL-5 | 0.023 | 0.93 |
| U2AF1 | |||
| CD4 + TLs | IFN-α | 0.007 | 0.78 |
| CD4 + TLs | IL-2 | 0.01 | 0.76 |
| CD4 + TLs | IL-5 | 0.046 | 0.64 |
| CD4 + TLs | IL-12p70 | 0.018 | 0.72 |
| CD4 + TLs | TNF-α | 0.039 | 0.66 |
| Treg | IL-6 | 0.04 | 0.65 |
| 5q- | |||
| NK TLs | TNF-α | 0.04 | -0.83 |