Supplementary Table 1. Curve extraction according to author 1 and 2.

Analysis	Study HR	Author 1- HR	Author 2- HR
DUO E ITT OS	0.77	0.76	0.79
DUO E ITT PFS	0.71	0.68	0.68
DUO E PMMR OS	0.91	0.93	0.92
DUO E DMMR OS	0.34	0.30	0.34
DUO E DMMR PFS	0.42	0.43	0.43
DUO E PMMR PFS	0.77	0.79	0.77
ATTEND DMMR OS	0.41	0.41	0.41
ATTEND DMMR PFS	0.36	0.37	0.38
ATTEND ITT OS	0.82	0.81	0.83
ATTEND ITT PFS	0.74	0.75	0.75
ATTEND PMMR OS	1.0	1.00	1.01
ATTEND PMMR PFS	0.92	0.92	0.92
MITO DMMR OS	NR	0.36	0.33
MITO DMMR PFS	0.46	0.37	0.39
MITO ITT OS	1.13	1.00	1.01
MITO ITT PFS	0.78	0.75	0.74
MITO PMMR OS	NR	0.54	0.53
MITO PMMR PFS	1.17	1.18	1.20
NRG DMMR PFS	0.30	0.30	0.32
NRG PMMR PFS	0.54	0.56	0.56
RUBY DMMR OS	0.32	0.35	0.34
RUBY DMMR PFS	0.28	0.33	0,36
RUBY ITT OS	0.69	0.65	0.69
RUBY ITT PFS	0.64	0.63	0.62
RUBY PMMR OS	0.79	0.78	0.78
RUBY PMMR PFS	0.76	0.75	0.76

Abbreviations: pMMR = proficient mismatch repair, dMMR = deficient mismatch repair, HR = Hazard ratio, PFS = progression-free survival, OS = Overall survival, NR: Not reported