Table 3.
Effect of Preoperative Biochemical and Routine Blood Tests on Patient Prognosis and Survival
| Parameters | N | Overall Survival (OS, N = 128) | t | P value | Progression-Free Survival (PFS, N = 128) | t | P value |
|---|---|---|---|---|---|---|---|
| AST | |||||||
| Normal | 92 | 22.43±17.54 | 8.568 | 0.004 | 7.16±8.61 | 2.253 | 0.136 |
| Abnormal | 36 | 12.78±14.63 | 4.72±7.31 | ||||
| ALT | |||||||
| Normal | 100 | 20.86±17.70 | 2.011 | 0.159 | 6.48±8.59 | 0.000 | 0.993 |
| Abnormal | 28 | 15.64±15.27 | 6.46±7.39 | ||||
| AST/ALT | |||||||
| Normal | 63 | 20.38±17.25 | 0.181 | 0.671 | 5.67±6.69 | 1.180 | 0.280 |
| Abnormal | 65 | 19.08±17.41 | 7.26±9.62 | ||||
| Total bilirubin | |||||||
| Normal | 81 | 22.36±17.99 | 5.324 | 0.023 | 7.15±8.55 | 1.445 | 0.232 |
| Abnormal | 47 | 15.17±15.08 | 5.32±7.84 | ||||
| Direct bilirubin | |||||||
| Normal | 40 | 18.58±17.03 | 0.254 | 0.615 | 5.90±8.44 | 0.278 | 0.599 |
| Abnormal | 88 | 20.24±17.46 | 6.74±8.29 | ||||
| Indirect bilirubin | |||||||
| Normal | 106 | 19.53±17.40 | 0.074 | 0.785 | 6.70±8.34 | 0.436 | 0.510 |
| Abnormal | 22 | 20.64±17.01 | 5.41±8.28 | ||||
| Albumin | |||||||
| Normal | 94 | 22.48±17.47 | 9.648 | 0.002 | 7.11±8.71 | 2.049 | 0.155 |
| Abnormal | 34 | 12.09±14.39 | 4.74±6.92 | ||||
| Creatinine | |||||||
| Normal | 79 | 21.15±17.26 | 1.425 | 0.235 | 7.15±8.87 | 1.366 | 0.245 |
| Abnormal | 49 | 17.41±17.23 | 5.39±7.29 | ||||
| Urea nitrogen | |||||||
| Normal | 109 | 19.18±17.43 | 0.703 | 0.403 | 6.13±7.93 | 1.291 | 0.258 |
| Abnormal | 19 | 22.79±16.49 | 8.47±10.28 | ||||
| Cholinesterase | |||||||
| Normal | 57 | 23.82±18.12 | 6.035 | 0.015 | 8.25±9.54 | 4.794 | 0.030 |
| Abnormal | 71 | 16.42±15.94 | 5.06±6.93 | ||||
| Coagulation PT | |||||||
| Normal | 36 | 15.47±13.76 | 3.076 | 0.082 | 4.97±4.75 | 1.649 | 0.201 |
| Abnormal | 92 | 21.38±18.27 | 7.07±9.30 | ||||
| Coagulation PTA | |||||||
| Normal | 93 | 20.43±17.03 | 0.575 | 0.45 | 6.68±8.10 | 0.197 | 0.658 |
| Abnormal | 35 | 17.83±18.02 | 5.94±8.94 | ||||
| Leukocyte | |||||||
| Normal | 51 | 17.14±16.33 | 7.053 | 0.009 | 6.37±8.14 | 0.053 | 0.819 |
| Abnormal | 43 | 25.82±18.12 | 6.74±8.82 | ||||
| Neutrophil absolute value | |||||||
| Normal | 100 | 18.10±16.81 | 4.112 | 0.045 | 6.79±8.59 | 0.648 | 0.422 |
| Abnormal | 28 | 25.50±17.98 | 5.36±7.26 | ||||
| Hemoglobin | |||||||
| Normal | 88 | 20.94±16.96 | 1.419 | 0.236 | 6.82±8.58 | 0.474 | 0.493 |
| Abnormal | 40 | 17.03±17.88 | 5.73±7.74 | ||||
| Platelet | |||||||
| Normal | 62 | 17.94±16.83 | 1.284 | 0.259 | 7.02±8.74 | 0.505 | 0.479 |
| Abnormal | 66 | 21.39±17.64 | 5.97±7.92 | ||||
| C-reactive protein | |||||||
| Normal | 74 | 26.64±16.66 | 35.828 | 0.000 | 8.92±9.93 | 17.060 | 0.000 |
| Abnormal | 54 | 10.24±13.21 | 3.13±3.92 | ||||
| Procalcitonin | |||||||
| Normal | 104 | 21.93±17.69 | 9.737 | 0.002 | 7.03±8.79 | 2.477 | 0.118 |
| Abnormal | 24 | 10.13±11.35 | 4.08±5.33 | ||||
| HBV DNA | |||||||
| Normal | 69 | 18.13±17.45 | 1.268 | 0.262 | 6.52±9.20 | 0.004 | 0.947 |
| Abnormal | 59 | 21.58±17.03 | 6.42±7.21 |
Notes: Normal range note: AST (17–59 U/L), ALT (<50 U/L), total bilirubin (3–22 µmol/L), direct bilirubin (0–5 µmol/L), indirect bilirubin (0–19 µmol/L), biochemical albumin (35–50 g/L), creatinine (58–110 µmol/L), blood urea nitrogen (3.2–7.1 mmol/L), cholinesterase (5900–12,220 <50 U/L), coagulation PT (9.4–12.5s), coagulation PTA (75–157%), blood routine albumin (3.5–9.5 × 10–9/L), blood routine neutrophil absolute value (1.8–6.3 × 10–9/L), hemoglobin (130–175 g/L), platelet count (125–350 × 10–9/L), and hepatitis B DNA (<1 × 10–2 IU/mL).