Table 4.
General effects of dequalinium chloride, bleomycin sulfate, pentamidine isethionate salt, and clioquinol against Cr. neoformans, Cr. deuterogattii, and Ca. auris.
| Antifungal activity | Morphological alterations | |||||
|---|---|---|---|---|---|---|
| Compound | Ca. auris | Cr. neoformans | Cr. deuterogattii | Ca. auris | Cr. neoformans | Cr. deuterogattii |
| Dequalinium chloride | Yesa | Yesb,c | Yesb,c | No | Yese | Yesf |
| Bleomycin sulfate | Yesa | Yesb,c | Yesb,c | Yesd | Yese | Yese |
| Pentamidine isethionate salt | Yesa | Yesb,c | Yesb,c | No | Yese | Yese |
| Clioquinol | Yesb,c | Yesb,c | Yesb,c | No | Yesf | No |
aActivity exclusive to the standard isolate using for drug screening.
bActivity against multiple isolates of the same species.
cFungicidal.
dInduction of hyphae-like morphology.
eCapsule reduction.
fCapsule enlargement.