Table 2.

Results of the MMRM Assessing the Effect of the Intervention on the Primary Outcome

Effect type	Parameter	Estimate	SE	t Value	95% CI
Fixed effects	Intercept (usual care at 3 mo)	82.835	1.197	69.208	80.549 to 85.103
	Age, y	−0.245	0.061	−4.009	−0.362 to −0.122
	Level of education	2.475	1.373	1.803	−0.189 to 5.169
	NIHSS score	0.218	0.219	0.999	−0.202 to 0.653
	Baseline HADS-D score	−0.665	0.188	−3.534	−1.041 to −0.304
	Baseline USER-P-R score	0.584	0.035	16.655	0.515 to 0.652
	Visit at 1 y	0.319	1.115	0.286	−1.869 to 2.502
	Intervention at 3 mo	1.894	1.693	1.119	−1.308 to 5.142
	Interaction visit by intervention at 1 y	−1.121	1.580	−0.709	−4.211 to 1.983
				Variance
Random effects	Between-participant variance			86.748
	Between-site variance			2.155
	Residual variance			150.213

Abbreviations: HADS-D = Hospital Anxiety and Depression Scale—Depression subscale; MMRM = mixed model for repeated measures; NIHSS = NIH Stroke Scale; USER-P-R = Restrictions subscale of the Utrecht Scale for Evaluation of Rehabilitation—Participation.