Table 3.
Primary Outcome and Secondary Outcomes
| Primary outcome at 1 y after stroke | Mean intervention | Mean usual care | Mean difference (95% CI) | p Value |
| USER-P-R score | 83.93 | 83.15 | 0.77 (−2.47 to 4.06) | 0.652 |
| Secondary outcomes at 3 mo after stroke | ||||
| USER-P-R score | 84.72 | 82.84 | 1.89 (−1.31 to 5.14) | |
| CLCE-24 cognition subscore | 2.34 | 2.54 | −0.21 (−0.59 to 0.18) | |
| CLCE-24 emotion subscore | 2.28 | 2.32 | −0.04 (−0.33 to 0.25) | |
| HADS-A subscore | 4.22 | 5.08 | −0.86 (−1.33 to −0.39) | |
| HADS-D subscore | 3.94 | 4.31 | −0.37 (−0.85 to 0.14) | |
| EQ-5D-5L index score | 0.842 | 0.799 | 0.044 (0.022 to 0.065) | |
| EQ-VAS score | 76.39 | 73.50 | 2.90 (0.69 to 5.10) | |
| PROMIS Global Physical Health T-score | 44.10 | 43.49 | 0.61 (−0.19 to 1.41) | |
| PROMIS Global Mental Health T-score | 45.68 | 45.65 | 0.03 (−1.03 to 1.09) | |
| GSES score | 33.80 | 32.84 | 0.97 (0.16 to 1.78) | |
| OR of treatment effect for unfavorable outcome (95% CI) | ||||
| mRS score | 1.96 | 1.99 | 1.13 (0.58 to 2.22) | |
| Secondary outcomes at 1 y after stroke | Mean difference (95% CI) | |||
| CLCE-24 cognition subscore | 2.81 | 2.84 | −0.03 (−0.42 to 0.36) | |
| CLCE-24 emotion subscore | 2.43 | 2.37 | 0.06 (−0.24 to 0.36) | |
| HADS-A subscore | 4.33 | 4.80 | −0.47 (−0.95 to 0.01) | |
| HADS-D subscore | 4.17 | 4.52 | −0.35 (−0.85 to 0.14) | |
| EQ-5D-5L index score | 0.831 | 0.788 | 0.043 (0.021 to 0.064) | |
| EQ-VAS score | 75.56 | 73.88 | 1.69 (−0.57 to 3.95) | |
| PROMIS Global Physical Health T-score | 43.83 | 43.32 | 0.51 (−0.31 to 1.32) | |
| PROMIS Global Mental Health T-score | 45.78 | 45.04 | 0.74 (−0.34 to 1.83) | |
| GSES score | 33.19 | 32.89 | 0.29 (−0.53 to 1.12) | |
| OR of treatment effect for unfavorable outcome (95% CI) | ||||
| mRS score | 1.79 | 1.97 | 0.78 (0.39 to 1.54) |
Abbreviations: CLCE-24 = Checklist for Cognitive and Emotional Consequences following Stroke; EQ-5D-5L = 5-level version of the EuroQol 5-dimensional questionnaire; EQ-VAS = EQ Visual Analog Scale; GSES = General Self-Efficacy Scale; HADS-A = Hospital Anxiety and Depression Scale—Anxiety subscale; HADS-D = Hospital Anxiety and Depression Scale—Depression subscale; mRS = modified Rankin Scale; OR = odds ratio; PROMIS = Patient-Reported Outcome Measurement Information System; USER-P-R = Restrictions subscale of the Utrecht Scale for Evaluation of Rehabilitation—Participation.