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. 2025 Mar 24;69(3):231–240. doi: 10.1159/000544973

Table 4.

Cytomorphological features in cell block specimens divided according to accurately and falsely diagnosed cases groups

Cytomorphological feature FN AUS (n = 17), n (%) FN SUMP (n = 5), n (%) TP BN (n = 21), n (%) p values between groups
Background Necrosis 1 (5.9) 0 (0.0) 0 (0.0) 0.457
Haemorrhage 9 (52.9) 1 (20.0) 9 (42.9) 0.421
Cystic haemorrhage 1 (5.9) 0 (0.0) 1 (4.8) 0.860
Inflammatory background 0 (0.0) 0 (0.0) 2 (9.5) 0.333
Lymphohistiocytic aggregates 2 (11.8) 0 (0.0) 9 (42.9) 0.035
Granular cystic debris 1 (5.9) 0 (0.0) 0 (0.0) 0.457
Macrophages 8 (47.1) 2 (40.0) 4 (19.0) 0.174
Lymphocytes 13 (76.5) 4 (80.0) 19 (90.5) 0.494
Plasma cells 0 (0.0) 0 (0.0) 3 (14.3) 0.185
Neutrophils 6 (35.3) 4 (80.0) 3 (14.3) 0.014
Adipocytes 1 (5.9) 0 (0.0) 0 (0.0) 0.457
Crystals, crystalloids 2 (11.8) 0 (0.0) 0 (0.0) 0.201
Debris 10 (58.8) 2 (40.0) 5 (23.8) 0.090
Keratin 2 (11.8) 0 (0.0) 0 (0.0) 0.201
Architecture Hypocellularity 1 (5.9) 0 (0.0) 0 (0.0) 0.457
Sheets 0 (0.0) 1 (20.0) 1 (4.8) 0.175
Formation of trabeculae 0 (0.0) 0 (0.0) 1 (4.8) 0.585
Papillae 1 (5.9) 0 (0.0) 20 (95.2) <0.001
Discohesivity 1 (5.9) 0 (0.0) 0 (0.0) 0.457
Single cells 1 (5.9) 1 (20.0) 0 (0.0) 0.154
Small groups 2 (11.8) 0 (0.0) 6 (28.6) 0.218
Cell Spindled cells 0 (0.0) 1 (20.0) 0 (0.0) 0.020
Oncocytic cells 10 (58.8) 3 (60.0) 21 (100.0) 0.004
Oncocytoid cells 1 (5.9) 1 (20.0) 0 (0.0) 0.154
Acini 2 (11.8) 0 (0.0) 0 (0.0) 0.201
Cytoplasmic granules 1 (5.9) 0 (0.0) 0 (0.0) 0.457
Nuclear Size variability 1 (5.9) 0 (0.0) 0 (0.0) 0.457

FN, false negative; TP, true positive; AUS, atypia of undetermined significance; SUMP, salivary gland neoplasm of uncertain malignant potential; BN, benign neoplasm.