Table 4.
Cytomorphological features in cell block specimens divided according to accurately and falsely diagnosed cases groups
| Cytomorphological feature | FN AUS (n = 17), n (%) | FN SUMP (n = 5), n (%) | TP BN (n = 21), n (%) | p values between groups | |
|---|---|---|---|---|---|
| Background | Necrosis | 1 (5.9) | 0 (0.0) | 0 (0.0) | 0.457 |
| Haemorrhage | 9 (52.9) | 1 (20.0) | 9 (42.9) | 0.421 | |
| Cystic haemorrhage | 1 (5.9) | 0 (0.0) | 1 (4.8) | 0.860 | |
| Inflammatory background | 0 (0.0) | 0 (0.0) | 2 (9.5) | 0.333 | |
| Lymphohistiocytic aggregates | 2 (11.8) | 0 (0.0) | 9 (42.9) | 0.035 | |
| Granular cystic debris | 1 (5.9) | 0 (0.0) | 0 (0.0) | 0.457 | |
| Macrophages | 8 (47.1) | 2 (40.0) | 4 (19.0) | 0.174 | |
| Lymphocytes | 13 (76.5) | 4 (80.0) | 19 (90.5) | 0.494 | |
| Plasma cells | 0 (0.0) | 0 (0.0) | 3 (14.3) | 0.185 | |
| Neutrophils | 6 (35.3) | 4 (80.0) | 3 (14.3) | 0.014 | |
| Adipocytes | 1 (5.9) | 0 (0.0) | 0 (0.0) | 0.457 | |
| Crystals, crystalloids | 2 (11.8) | 0 (0.0) | 0 (0.0) | 0.201 | |
| Debris | 10 (58.8) | 2 (40.0) | 5 (23.8) | 0.090 | |
| Keratin | 2 (11.8) | 0 (0.0) | 0 (0.0) | 0.201 | |
| Architecture | Hypocellularity | 1 (5.9) | 0 (0.0) | 0 (0.0) | 0.457 |
| Sheets | 0 (0.0) | 1 (20.0) | 1 (4.8) | 0.175 | |
| Formation of trabeculae | 0 (0.0) | 0 (0.0) | 1 (4.8) | 0.585 | |
| Papillae | 1 (5.9) | 0 (0.0) | 20 (95.2) | <0.001 | |
| Discohesivity | 1 (5.9) | 0 (0.0) | 0 (0.0) | 0.457 | |
| Single cells | 1 (5.9) | 1 (20.0) | 0 (0.0) | 0.154 | |
| Small groups | 2 (11.8) | 0 (0.0) | 6 (28.6) | 0.218 | |
| Cell | Spindled cells | 0 (0.0) | 1 (20.0) | 0 (0.0) | 0.020 |
| Oncocytic cells | 10 (58.8) | 3 (60.0) | 21 (100.0) | 0.004 | |
| Oncocytoid cells | 1 (5.9) | 1 (20.0) | 0 (0.0) | 0.154 | |
| Acini | 2 (11.8) | 0 (0.0) | 0 (0.0) | 0.201 | |
| Cytoplasmic granules | 1 (5.9) | 0 (0.0) | 0 (0.0) | 0.457 | |
| Nuclear | Size variability | 1 (5.9) | 0 (0.0) | 0 (0.0) | 0.457 |
FN, false negative; TP, true positive; AUS, atypia of undetermined significance; SUMP, salivary gland neoplasm of uncertain malignant potential; BN, benign neoplasm.