Table 5.
Associations between average length of each night shift and risk of cholelithiasis (n = 62,558).
| Variables | HR (95% CI) by average length of each night shift during night shift periods | P for trend | |||
|---|---|---|---|---|---|
| None | ≤8h | 8-12h | ≥12h | ||
| Cases | 1122 | 166 | 126 | 164 | |
| Person-years | 645107.98 | 76709.80 | 56175.72 | 71364.23 | |
| Incidence rate* | 17.39 | 21.64 | 22.43 | 22.98 | |
| Model 1 | 1.00 (ref) | 1.40 (1.18-1.65) | 1.29 (1.07-1.55) | 1.38 (1.17-1.63) | <0.001 |
| Model 2 | 1.00 (ref) | 1.27 (1.07-1.51) | 1.18 (0.97-1.42) | 1.30 (1.09-1.53) | <0.001 |
| Model 3 | 1.00 (ref) | 1.23 (1.04-1.46) | 1.16 (0.95-1.40) | 1.25 (1.06-1.48) | 0.002 |
ref= reference.
*Per 10,000 person-years.
Model 1 stratified for age, sex and UK Biobank assessment centers; Model 2 further adjusted for race, index of multiple deprivation and education level; Model 3 adjusted for terms in Model 2 and health rating, long-standing illness, multivitamin use and mineral use.