Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Schematic representation of the current working hypothesis. CYP1A1 enzymatic activity converts the endogenous CYP1A1 substrate (S) to an inactive product (P). Substrate-bound AHR dimerizes with ARNT, and the AHR-ARNT complex transactivates Cyp1a1 and other target genes.
