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. 1998 Jan;18(1):525–535. doi: 10.1128/mcb.18.1.525

TABLE 1.

Pertinent phenotypes of cell lines used in these experiments

Cell line Derivation Phenotype Reference
Hepa-1 C57BL/6 mouse hepatoma AHR+ ARNT+ CYP1A1+; wild-type 3
c37 Hepa-1 AHR+ ARNT+ CYP1A1; two nonsense mutations in the Cyp1a1 gene 24, 33
CX4 c37 AHR+ ARNT+ CYP1A1+; c37 stable transfectant of plasmid-encoded wild-type mouse CYP1A1 cDNA 56, 57
CH3.3 c37 AHR+ ARNT+ CYP1A1 CYP1A2+; c37 stable transfectant of plasmidencoded wild-type human CYP1A2 cDNA 56, 57
CPr c37 AHR+ ARNT+ CYP1A1; c37 stable transfectant of a plasmid with enhancerless mouse CYP1A1 cDNA 56, 57
CV-1 African green monkey kidney AHR ARNT+a CYP1A1 31
a

ARNT+ phenotype is weakly expressed in CV-1 cells.