TABLE 3.
Induction of AHR–ARNT-dependent reporter gene expression by Ellipticine in Hepa-1 cells stably transfected with pAhRDtkLuc3
| Treatment | Luciferase activity/μg of protein (avg ± SD) | Pa |
|---|---|---|
| 0.1% DMSO | 11.9 ± 1.3 | |
| 10 nM Ellipticine | 21.3 ± 0.0 | >0.05 |
| 100 nM Ellipticine | 41.5 ± 2.1 | <0.0001 |
| 10 nM TCDD | 66.8 ± 9.6 | <0.0001 |
Bonferroni P value for one-way analysis of variance of comparisons to DMSO-treated control.