Table 1.
Characteristics of patients.
| EHOA (n = 138) | RA (n = 379) | P value | |
|---|---|---|---|
| Female, n (%) | 113 (81.9 %) | 289 (76.3 %) | 0.174 |
| Years, median (IQR) | 67.3 (64.3, 72.2) | 48.6 (39.3, 55.6) | <0.001 |
| Body mass index, median (IQR) | 24.8 (22.2, 27.3) | 25.5 (22.4, 28.7) | <0.001 |
| Socio educational level, n (%) | <0.001 | ||
| Higher education | 77 (55.8 %) | 344 (90.8 %) | – |
| Secondary education | 45 (32.6 %) | 0 (0 %) | – |
| Primary education | 16 (11.6 %) | 35 (9.2 %) | – |
| Current smoker, n (%) | 9 (6.5 %) | 63 (16.6 %) | 0.002 |
| Current alcohol consumption, n (%) | 106 (76.8 %) | 60 (15.8 %) | <0.001 |
| Disease duration, median year (IQR) | 13.5 (7.0, 20.0) | 10.5 (10.3, 10.7) | 0.003 |
| RF IgM-positive, n (%) | 7 (5.1 %) | 219 (57.8 %) | <0.001 |
| ACPA positivity, n (%) | – | 206 (54.4 %) | – |
| Sharp-van der Heijde score, median (IQR)a | – | 5.3 (2.0, 14.8) | – |
| DAS 28 CRP, median (IQR)b | – | 2.3 (1.6, 3.2) | – |
| CRP ≥ 5 mg/L, n (%)c | 11 (8.0 %) | 119 (32.2 %) | <0.001 |
| Treatments, n (%) | |||
| Salazopyrine, Leflunomide or Hydroxchloroquine | – | 179 (47.2 %) | – |
| Methotrexate | – | 310 (81.8 %) | – |
| Biological Dmards | – | 140 (36.9 %) | – |
| Glucorcorticoids during the past year, n(%)d | 2 (1.4 %) | 96 (25.3 %) | <0.001 |
| Mean dose a day, median (IQR)d | 1.5 (1.3, 1.8) | 4 (1.1, 5.0) | 0.301 |
| Non steroidal anti inflammatory drugs, n (%) (%) | 28 (20.3 %) | 128 (33.8 %) | 0.003 |
| Opioids, n (%) | – | 1 (0.3 %) | – |
| Number of comorbidities, n (%) | 0.002 | ||
| 0 | 33 (23.9 %) | 143 (37.7 %) | |
| 1 | 53 (38.4 %) | 132 (34.8 %) | |
| 2 | 40 (29.0 %) | 62 (16.4 %) | |
| ≥ 3 | 12 (8.7 %) | 42 (11.1 %) | |
| Hepatitis virus B or C, n (%) | 1 (0.7 %) | 8 (2.1 %) | 0.456 |
| High blood pressure, n (%) | 89 (64.5 %) | 111 (29.3 %) | <0.001 |
| Dyslipidemia, n (%) | 52 (37.7 %) | 155 (40.9 %) | 0.543 |
| Diabete, n (%) | 10 (7.2 %) | 34 (9.0 %) | 0.600 |
| Myocardial infarction, n (%) | 1 (0.7 %) | 11 (2.9 %) | 0.196 |
| Stroke, n (%) | 4 (2.9 %) | 7 (1.8 %) | 0.495 |
| Neoplasia, n (%) | 16 (11.6 %) | 39 (10.3 %) | 0.747 |
| Hemopathy, n (%) | 0 (0.0 %) | 4 (1.1 %) | 0.578 |
| Spine fracture, n (%) | 0 (0.0 %) | 7 (1.8 %) | 0.180 |
| Other fracture, n (%) | 0 (0.0 %) | 31 (8.2 %) | <0.001 |
EHOA = erosive hand osteoarthritis; RA = Rheumatoid arthritis. Data are expressed as number (percent) or median and interquartile interval. P values are Tisher's exact test or Wilcoxon rank test, depending on the variable. Missing value in the RA population.
a
N = 87.
b
N = 28.
c
N = 10.
d
N = 283.