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. 2025 May 31;26(11):5304. doi: 10.3390/ijms26115304
ABC ATP-binding cassette
Andosan™ Water extracts of the mycelia of Agaricus blazei (82.4%), Hericeum erinaceus (14.7%), and Grifola frondosa (2.9%)
BAX Bcl-2-associated x, apoptosis regulator
Bcl-2 B-cell lymphoma 2
BIRC5 Baculoviral IAP repeat-containing 5
BSGLWE Sporoderm-broken spores of G. lucidum water extract
Caco-2 Human colorectal adenocarcinoma cell line
CBAEP Cibacron blue affinity eluted protein
CCNB1 Cyclin B1
CCNE1 Cyclin E1
CDK1 Cyclin-dependent kinase 1
COLO-205 Human colorectal adenocarcinoma cell line 205
COX-2 Cyclooxygenase-2
CRC Colorectal cancer
CRISPR Clustered regularly interspaced short palindromic repeats
DNA Deoxyribonucleic acid
ERK Extracellular signal-regulated kinase
FIP Fungal immunomodulatory protein
GIPS Polysaccharides purified from Gloeostereum incarnatum
GLE Ganoderma Lucidum extract
GLP Ganoderma lucidum polysaccharides
GLSF Ganoderma lucidum extract containg spores and fruiting bodies (30:8 ratio)
HCT-116 Human colorectal carcinoma cell line 116
HIF-1α or HIF1A Hypoxia-inducible factor-1 alpha
HT-29 Human colorectal adenocarcinoma cell line 29
hTERT Human telomerase reverse transcriptase
IkappaB-α NF-kappa-B inhibitor alpha
IL Interleukin
LAP Lentinus edodes alcohol precipitate
LEM Lentinus edodes mycelium extracts
MDR1 Multidrug resistance protein 1
MEK Mitogen-activated protein kinase
MM Medicinal mushrooms
MMP-2 Matrix metallopeptidase-2
MRP1 Multidrug resistance-associated protein 1
NAG-1 Nonsteroidal anti-inflammatory drug-activated gene-1
NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells
NK cells Natural killer cells
Nrf2 Nuclear factor erythroid 2
p21/Cip1 or CDKN1A Cyclin-dependent kinase inhibitor 1
p27/Kip1 or CDKN1B Cyclin-dependent kinase inhibitor 1B
p53 Tumor protein p53
PARP Poly (ADP-ribose) polymerase
PSC-hex n-hexane fraction of Pleurotus sajor-caju
RAF-1 RAF proto-oncogene serine/threonine-protein kinase
ROS Reactive oxygen species
SLNT Water-extracted polysaccharide from Lentinus edodes
SW-480 Surg pathol-derived colorectal cancer cell line 480
SW620/Ad300 Surg pathol-derived colorectal cancer cell line 620
TGF-β Transforming growth factor beta
THP-1 Tohoku Hospital Pediatrics-1 human monocytic leukemia cell line
TNF-α Tumor necrosis factor alpha
WAAP A homogeneous neutral polysaccharide