| ACTH | Adrenocorticotropic Hormone |
| ADME | Absorption, Distribution, Metabolism, Excretion |
| AIS | Athens Insomnia Scale |
| API | Active Pharmaceutical Ingredient |
| BDI | Beck Depression Inventory |
| BIS/BAS | Behavioral Inhibition System/Behavioral Activation System |
| BL-VAS | Bond–Lader Visual Analog Scale |
| CAR | Cortisol Awakening Response |
| CANTAB | Cambridge Neuropsychological Test Automated Battery |
| CFS | Chalder Fatigue Scale |
| CYP | Cytochrome P450 |
| EEG | Electroencephalogram |
| ENS | Enteric Nervous System |
| EAT | Eating Attitudes Test |
| ESS | Epworth Sleepiness Scale |
| FAST™ | Fatigue Avoidance Scheduling Tool |
| FFQ | Food Frequency Questionnaire |
| FMT | Fecal Microbiota Transplantation |
| GABA | γ-Aminobutyric Acid |
| GAD | Generalized Anxiety Disorder |
| GASS | Glasgow Antipsychotic Side-effect Scale |
| GH | Growth Hormone |
| GHQ | General Health Questionnaire |
| GI-VAS | Gastrointestinal Visual Analogue Scale |
| Glu | Glutamate |
| HADS | Hospital Anxiety and Depression Scale |
| HAMA-14 | Hamilton Anxiety Rating Scale-14 |
| HDRS-17 | Hamilton Depression Rating Scale-17 |
| HDT | Head-Down Tilt |
| HLU | Hindlimb Unloading |
| IBD | Inflammatory Bowel Disease |
| IBS | Irritable Bowel Syndrome |
| IPAQ | International Physical Activity Questionnaire |
| ipRGCs | Intrinsically Photosensitive Retinal Ganglion Cells |
| ISI | Insomnia Severity Index |
| ISS | International Space Station |
| LED | Light-Emitting Diode |
| LEIDS-R | Leiden Index of Depression Sensitivity-Revised |
| LIR | Lymphocyte Irradiation Response |
| LOT-R | Life Orientation Test-Revised |
| MDA | Malondialdehyde |
| MEQ | Morningness–Eveningness Questionnaire |
| MGBA | Microbiota–Gut–Brain Axis |
| MPSs | Microphysiological Systems |
| NASA | National Aeronautics and Space Administration |
| NSBRI | National Space Biomedical Research Institute |
| OSA | Obstructive Sleep Apnea |
| PASA | Post-Acute Stress Assessment |
| PBPK | Physiologically Based Pharmacokinetic |
| PD | Pharmacodynamics |
| PHQ | Patient Health Questionnaire |
| PK | Pharmacokinetics |
| POMS | Profile of Mood States |
| PSG | Polysomnography |
| PSQI | Pittsburgh Sleep Quality Index |
| PSS | Perceived Stress Scale |
| REM | Rapid Eye Movement |
| RCSQ | Richards–Campbell Sleep Questionnaire |
| SAS | Self-Rating Anxiety Scale |
| SCFAs | Short-Chain Fatty Acids |
| SCN | Suprachiasmatic Nucleus |
| SDS | Self-Rating Depression Scale |
| SF-36 | 36-Item Short Form Health Survey |
| SOD | Superoxide Dismutase |
| SRI | Stress Response Inventory |
| SRSS | Self-Rating Sleep Scale |
| SSLA | Solid-State Lighting Assemblies |
| STAI | State–Trait Anxiety Inventory |
| SWS | Slow-Wave Sleep |
| TCI | Temperament and Character Inventory |
| TCM | Traditional Chinese Medicine |
| USP | United States Pharmacopeia |
| VAS | Visual Analogue Scale |
| VSH | Verran Snyder–Halpern Sleep Scale |
| WASO | Wake After Sleep Onset |