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. 2025 May 24;17(11):1784. doi: 10.3390/nu17111784

Table 1.

Some foods that can lower blood lipids.

Food Name Bioactive Components Mechanisms Ref.
Natto Nattokinase Serum triglyceride, total cholesterol, and low-density lipoprotein cholesterol (LDL-C) levels were significantly reduced. [58]
Mulberry Ethyl acetate Reduces serum triglyceride (TG), total cholesterol (TC), and low-density lipoprotein cholesterol (LDL-C) levels, thereby preventing atherosclerosis. [59]
Citrus Naringin Increases anti-lipid peroxidation in liver, decreases SOD activity and oxygen free radical generation, and significantly reduces MDA content. [60]
Sea Buckthorn Fruit Quercetin Promotes the conversion of cholesterol into bile acids, promotes cholesterol efflux, inhibits cholesterol de novo synthesis, and accelerates fatty acid oxidation. [61]
Hawthorn Hypericin and
Ursolic acid
Can prevent the accumulation of fat in the liver, affect the PPARr-PPRE signaling system, and inhibit the synthesis of endogenous lipids. [62]
Garlic Garlicn The levels of serum TC, TG, and LDL-C were significantly decreased, and the content of high-density lipoprotein cholesterol (HDL-C) was increased. The activities of serum lecithin cholesterol acyltransferase, myocardial lipoprotein lipase, and hepatic lipase were increased to varying degrees. [63]
Onion Onion alcohol extract Increases the expression of LDLR protein and reduces the expression of HMG CR protein to play its lipid-lowering effect. [64]
Capsicum Capsaicin Promotes the secretion of the nerve conduction substances acetylcholine and thyroid gland, and promotes body fat oxidation. [65]
Tomato Lycopene Inhibits acyl-CoA. [66]
Yam Yam polysaccharide Improves the activity of total superoxide dismutase (T-SOD), catalase, insulin sensitivity, and antioxidant activity. [67]