Table 2. Relationships between the BPRI and clinical outcomes in different models.
| BPRI | Model 1 | Model 2 | Model 3 | Model 4 | ||||
|---|---|---|---|---|---|---|---|---|
| OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | OR (95% CI) | P value | |
| In-hospital mortality | 0.978 (0.974, 0.982) | <0.0001 | 0.978 (0.974, 0.982) | <0.0001 | 0.978 (0.974, 0.983) | <0.0001 | 0.975 (0.971, 0.980) | <0.0001 |
| Quartile | ||||||||
| Quartile 1 | Ref | Ref | Ref | Ref | ||||
| Quartile 2 | 0.413 (0.357, 0.478) | <0.0001 | 0.409 (0.352, 0.474) | <0.0001 | 0.474 (0.405, 0.555) | <0.0001 | 0.518 (0.437, 0.613) | <0.0001 |
| Quartile 3 | 0.315 (0.270, 0.367) | <0.0001 | 0.321 (0.274, 0.375) | <0.0001 | 0.395 (0.334, 0.466) | <0.0001 | 0.412 (0.345, 0.492) | <0.0001 |
| Quartile 4 | 0.300 (0.257, 0.351) | <0.0001 | 0.293 (0.250, 0.343) | <0.0001 | 0.305 (0.257, 0.361) | <0.0001 | 0.280 (0.233, 0.337) | <0.0001 |
| P for trend | <0.0001 | <0.0001 | <0.0001 | <0.0001 | ||||
| 28-day mortality | 0.980 (0.976, 0.985) | <0.0001 | 0.980 (0.976, 0.984) | <0.0001 | 0.980 (0.976, 0.984) | <0.0001 | 0.980 (0.975, 0.984) | <0.0001 |
| Quartile 1 | Ref | Ref | Ref | Ref | ||||
| Quartile 2 | 0.415 (0.359, 0.479) | <0.0001 | 0.408 (0.352, 0.473) | <0.0001 | 0.467 (0.400, 0.546) | <0.0001 | 0.520 (0.441, 0.613) | <0.0001 |
| Quartile 3 | 0.331 (0.285, 0.385) | <0.0001 | 0.337 (0.289, 0.392) | <0.0001 | 0.406 (0.346, 0.478) | <0.0001 | 0.445 (0.375, 0.528) | <0.0001 |
| Quartile 4 | 0.315 (0.270, 0.366) | <0.0001 | 0.305 (0.262, 0.356) | <0.0001 | 0.317 (0.269, 0.374) | <0.0001 | 0.321 (0.269, 0.383) | <0.0001 |
| P for trend | <0.0001 | <0.0001 | <0.0001 | <0.0001 | ||||
| 90-day mortality | 0.984 (0.981, 0.988) | <0.0001 | 0.984 (0.980, 0.987) | <0.0001 | 0.984 (0.980, 0.988) | <0.0001 | 0.982 (0.978, 0.986) | <0.0001 |
| Quartile 1 | Ref | Ref | Ref | Ref | ||||
| Quartile 2 | 0.475 (0.415, 0.545) | <0.0001 | 0.466 (0.405, 0.537) | <0.0001 | 0.543 (0.467, 0.631) | <0.0001 | 0.607 (0.518, 0.711) | <0.0001 |
| Quartile 3 | 0.368 (0.319, 0.423) | <0.0001 | 0.370 (0.320, 0.428) | <0.0001 | 0.452 (0.387, 0.527) | <0.0001 | 0.490 (0.416, 0.577) | <0.0001 |
| Quartile 4 | 0.369 (0.320, 0.424) | <0.0001 | 0.351 (0.304, 0.407) | <0.0001 | 0.373 (0.319, 0.436) | <0.0001 | 0.361 (0.305, 0.427) | <0.0001 |
| P for trend | <0.0001 | <0.0001 | <0.0001 | <0.0001 | ||||
OR, odds ratio; CI, confidence interval; Ref, reference; Model 1: Adjusted for age, sex, ethnicity and weight. Model 2: Adjusted for variables included in Model 1 + myocardial infarction, congestive heart failure, cerebrovascular disease, chronic pulmonary disease, diabetes without control, severe liver disease, malignant cancer and renal disease.
Model 3: Adjusted for variables included in Model 2 + Charlson comorbidity index, SOFA score, SAPSII score, SBP, DBP, MAP, heart rate, respiratory rate, temperature and SpO2. Model 4: Adjusted for variables included in Model 3 + white blood cell count, hemoglobin, platelet count, anion gap, bicarbonate, chloride, glucose, sodium, potassium, creatinine, blood urea nitrogen, calcium and prothrombin time, invasive ventilation, RRT and AKI.