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. 2025 Jun 12;39(12):e70708. doi: 10.1096/fj.202402377R

FIGURE 2.

FIGURE 2

Basal physiological autophagic flux is intrinsically different in different cell types. Flow cytometry histogram representing LC3B‐II fluorescent signal in whole blood treated with or without CQ (A). Summary data of LC3B‐II flux in different cell populations, including T cells, B cells, NK cells, monocytes, and others (B). Histogram of LC3B‐II levels of monocyte subpopulations in whole blood treated with or without CQ including classical, intermediate, and nonclassical monocytes (C). Summary data of LC3B‐II flux in different subpopulations including Monocyte (D), NK cells (E), B cells (F), T cells (G), CD4 T cells (H), CD8 T cells (I). Measurement of LC3B‐II flux was performed in N = 43 people. Friedman test with multiple comparison and Wilcoxon matched‐paired signed rank test analysis were used. *p < 0.05, **p < 0.01, ***p < 0.001). Bars = median. Datapoints = participants.