Figure 1.

Axial T2-weighted magnetic resonance images of the brain at the level of the basal ganglia. A, Patient with PMLD at 6 years of age (patient III:3; fig. 3). B, Patient with PMD at 7 years of age. The patients in panels A and B show nearly identical hypomyelination patterns of central white matter, as indicated by diffusely enhanced signal intensity. C, Low signal of normal myelination in an unaffected child.