Table 4.

Analysis of Alleles Causing NLSDs^[Note]

Locus	Allele	Marker	Referencea	x	i	jo	pN	θ	Pr(j⩾jo)	Pr(m⩽1)When tF=26	Pr(m⩽1)When tF=77.2
BRCA1	185delAG	D17S1320	Neuhausen et al. 1996	.01	15	15	.27	.005	.26	.15	.97
BLM	blmAsh	D15S1108	Ellis et al. 1998	.0047	52	43	.1b	.00025	.98	.58	.97
DYS	2057+6T→Cc	D9S261	Blumenfeld et al. 1999	.0158	435	403	.53	.008	.33	.02	.93
ITY1	GAG deletiond	ASS	Risch et al. 1995b	.0005	54	47	.09	.018	.07	.98	.99
LDLR	G197del	D19S865	Durst et al. 2001	.0074	37	26	.22	.026	.21	.22	.99

Note.— All results are based on 10,000 replicates with N₀=3,000 and N₁=600.

^aReferences are to the articles from which the genetic parameters (x, i, j_o, p_N, and θ) were extracted.

^bAncestral marker allele frequency not available. Similar results were obtained for other values of p_N.

^cCausative allele was identified and named by Anderson et al. (2001).

^dCausative allele was identified by Ozelius et al. (1997).