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. 2025 May 13;17(5):e84020. doi: 10.7759/cureus.84020

Table 4. Treatment administered to study participants by type of metastasis, n (%).

CDK4/6-i: CDK4/6 inhibitors; EC: epirubicin and cyclophosphamide; HT: hormone therapy; RT: radiotherapy; SLNB: selective lymph node biopsy.

Variables Overall (n = 17) Oligometastatic (n = 12) Multimetastatic (n = 5)
Initial systemic treatment      
 EC + Taxanes 4 (24) 4 (33) 0 (0)
 EC + Taxanes + Carboplatin 1 (6) 1 (8) 0 (0)
 EC + Taxanes + Anti-HER2 2 (12) 2 (17) 0 (0)
 Taxanes + Anti-HER2 4 (24) 1 (8) 3 (60)
 HT 1 (6) 0 (0) 1 (20)
 HT + CDK4/6-i 5 (29) 4 (33) 1 (20)
Local ablative treatment      
 Primary      
  Tumourectomy 2 (12) 0 (0) 2 (40)
  Tumourectomy + SLNB 2 (12) 2 (17) 0 (0)
  Tumourectomy + Lymphadenectomy 3 (18) 3 (25) 0 (0)
  Mastectomy + SLNB 1 (6) 1 (8) 0 (0)
  Mastectomy + Lymphadenectomy 7 (41) 5 (42) 2 (40)
  RT 2 (12) 1 (8) 1 (20)
 Metastatic      
  None 9 (53) 5 (42) 4 (80)
  RT bone M1 5 (29) 5 (42) 0 (0)
  RT nodal M1 2 (12) 1 (8) 1 (20)
  RT nodal and bone M1 1 (6) 1 (8) 0 (0)
Adjuvant treatment      
 RT 6 (35) 5 (42) 1 (20)
 RT + Anti-HER2 1 (6) 0 (0) 1 (20)
 RT + HT 2 (12) 2 (17) 0 (0)
 HT 2 (12) 2 (17) 0 (0)
 RT + Anti-HER2 + HT 1 (6) 1 (8) 0 (0)
 None 5 (29) 2 (17) 3 (60)