. 2007 Jul 25;133(11):809–815. doi: 10.1007/s00432-007-0281-2

Table 2.

Viral load as a prognostic marker in areas of low and high incidence of EBV-associated tumors and its relationship with overall survival (OS) of patients suffering from EBV-associated cancers

Reference	Type of tumor	No. of patients	Type of the study	Prognosis according to EBV DNA levels or positivity	Clinical cut-off
Chan et al. (2003)	UCNT	170	Prospective	<4,000 copies OS 1 y = 93%, >4,000 copies OS = 48%	4,000 EBV DNA copies
Le et al. (2005)	UCNT	58	Prospective	EBV DNA—OS 2 ys = 94%, EBV DNA+ OS = 55%	EBV DNA+
Lin et al. (2004)	UCNT	99	Prospective	<1,500 copies OS 2 ys = 100%, >1,500 copies OS = 83.4%	1,500 EBV DNA copies
Twu et al. (2007)	UCNT	114	Prospective	EBV DNA—OS 4 ys = 100%, EBV DNA+ OS = 63%	EBV DNA+
Au et al. (2004)	NK/T cell lymphomas	23	Prospective	<6.1 × 10⁷ copies OS = 54 months, >6.1 × 10⁷ copies OS = 2.1 months	6.1 × 10⁷ copies

UCNT undifferentiated carcinoma of nasopharyngeal type, NK/T Natural Killer/T, y year, ys years